July 12, 2005

"Human Genome and Everyday Life"

David R. Cox, MD, Ph.D.

Chief Scientific Officer
Perlegen Sciences, Inc.

Dr. Cox is internationally recognized for his research on the molecular basis of human genetic disease. The search for a cost effective method to analyze human DNA variations led Dr. Cox to leave his position as a Professor of Genetics and Pediatrics at the Stanford University School of Medicine in 2000 to found Perlegen Sciences. Perlegen has developed sophisticated technology to analyze rapidly millions of individual single nucleotide polymorphisms (SNPs) in thousands of individuals. This approach to pharmacogenomics will allow to understand the way in which variations in DNA sequences contribute to traits such as common diseases and drug responses. Pelergen has characterized whole-genome patterns of common human DNA variation by genotyping 1,586,383 SNPs in 71 Americans of European, African, and Han Chinese ancestry. In total, more than 112 million individual genotypes (click here to access Perlegen Genotype Browser) were determined in a timeframe of months rather than years.